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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a357e01e71b7512e62a0808399993f514694517620f2dee56b0b7f8c205e230c' 
  AND token = 'JmboBv5mBYCRpMNWRP1oU8sMWH+o1G56lcHB/ZGvbYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}