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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d1442abf125a412b2ba6e4afe931e39d2c9680940bb5d5464c9e24ab839455' 
  AND token = '2M3P9t+Hgwg1hZt3xP+vHjXv52OtWqKgNTzgR1CE2fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}