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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53927db0e0ac072d6cd5365e2a250499a1468ff257f4112c07c523930a3ad2cd' 
  AND token = 'UCaq/q9D6/0aiKBE/GcLaONGM5yl70Vyi1y17prjvhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}