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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd72d6afed4c2c5b30a893003cb90a6b080de7431de7363e4125c7b3317a97259' 
  AND token = 'MZF12RogxlgroITJEbgBaK0zSgG1VdKREOe8Kf/LKRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}