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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f1cbb35f1c03c71d51694d738449c8aa9f480805e728f5d9f7c142dda31e0c1' 
  AND token = 'DGXnW1WLT4HbjHttaJDyVyhrgx+nBQ9XPd0YpLcIvDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}