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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6143599ca0288f7e434b478c38094cf8a3bf29fd3faa9212fd57c85849993b75' 
  AND token = 'T77UKHPuBAepGeaIkS9Q5i01RYxFwd+ogf7M1BIXrvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}