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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7daa6e5087882ada69a0fbf4cab63e526d9b0d994aab1023876cc206605da6e' 
  AND token = 'kKBLQMqRPYmndb4opsc/SdcxIWm3WFLKww1AIVuq/WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}