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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '881eda1e31e5c922400cada5c62cc1c08e0aeaad199d12243294370c50a35641' 
  AND token = 'fPucvq2JDik9asRdrA75Sy/GWTweyTOWpsnWRk0neWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}