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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4093c714ddbc9795dafcfb2718fa73e5ef7f2240ee2e3cb770d13de504498096' 
  AND token = 's01C61L3IypdeTtEhZAHuueBrAQcmqozJDpkPYYZjZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}