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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7abef2f905970cca7e0ef574b7cb33c214320c4a358601983052d043ed557ade' 
  AND token = 'zuss4gNUDPl34ED1z8pRTVp+PVdvM1IW9i9dihTzpHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}