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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '487f50f976b5391f156c0409820faf6e383a50c7cd1c237a717743e9f9b69ff3' 
  AND token = '4LoC1vBG98HlCMRAsCofbTZoUIKkouyT8kDdfA025No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}