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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86d80a4bedeb7c7ef455e095a352756351d80aa113fc6db3c1c25e8fefbc55a4' 
  AND token = 'xWW+gJerQigdNr+KdUnEw7aWsEAu0IylrYjoy+jbT1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}