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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce497af00122c9a5cbead8d627e550d4ec08c2c2db7550566e6f0490b2370de3' 
  AND token = 'SZfezq0Gq3IVJn7VDQJNEeLgZ/RcNYJ1PkQkyZF8YtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}