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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3282f0ae64a88334d5998d8e21f343efcac0453ff63e6d63ed978906ed1dd501' 
  AND token = 'I46deXpfzN3Rv0qot83au7VIujpqPiRxsriq7T9afBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}