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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d9dccbc18e7a26ff607f49d96376258de6bdacc63a8de41a6d710a6838edf7' 
  AND token = 'N9Y1CWmoz17/ZB+mIk9lexQ4p3mYoE0jFmAuop4rtkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}