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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18bc7cc5dccd931fc6a2612e60436c011c3a6cf79d816b1355534f8b53b76026' 
  AND token = 'rzfDmMQ0nQipsIEa82vP1cs3AXX6I3tcVjYzSw5QIv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}