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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3bc5e0f94c4d2b280748ee91372060c1d4710d52eab055552b0806e4232c537' 
  AND token = 'W4rtZIwyn4gVKK+e4L053vkeRVKAL2IIG2mtetM/aVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}