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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '330e4cbcef1bf7759a2c6ada753274b57236aa972ab40b5c0586cc44f5660edb' 
  AND token = 'O55Khx1e/t0wUOxwg/6Xh0s/Vjbn//Mp+T5ii3hfUZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}