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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd41a643944579c46a9eabcd7bfc92b0179d6cf234114e8cb06bac8930b65f2d0' 
  AND token = 'nNkRXvUg9A8gyjFefQrpsWHZnTs1ec49hQLlpT2wDNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}