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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a693c43b09b838887fe88d12a1e011d3e48f483493ebc29767ac8c58d1a66c' 
  AND token = 'ea+wJO6RFyzIdTZ+L3drb0jrli+23EZtRRHuTBDYIAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}