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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4acbb49f5747f3b562f54ed34d388a20d9c88be943cbb3639266431afd824da3' 
  AND token = 'nfrCQPBd7xBO8wDjxuHqg+CvBWFpHEfg1EEFTrtyETg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}