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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af16152db8297731d37050199948511dae6972ce27d7e8e9b2905c1f860a21af' 
  AND token = '0yjQi1PFj4niIMhDw0ukBCjVu6GuVUfA0fMoszRVp4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}