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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b1cc6dbbaad291aaa82235f11d9aaec67254b068003e0f42be8e8660e62e37' 
  AND token = 'pg2dEnS6SvtvHtJZn3Ad048+6jlVffUFAn7c0NrLwwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}