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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ec0aaf3635479c8ddaa49e4f5f16c9e4f5640354c7c244dad13a7207fb080d2' 
  AND token = 'P5cZbmRi2xix2HLducPdMshdLnP0arIsKNklN7MihWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}