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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9654335a42a70693e31053e14359d8a0c07aad27113b59fdbfb0ed27d48452df' 
  AND token = 'MKCcUJm1/hsZCKCeTKJ0tiOgsxMAb8s2tgL4sB3hN18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}