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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88cfd86ab3adacc35b17566ca592d2f25244c896c6396941ba568c1f04ed6dc4' 
  AND token = 'AegaK+QQHcswtUozBo5AeCJhCnt3VX6ML4fPt+qT1Js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}