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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88ba36e9bd2326f2b6fcbf1d70a657d35975c8a39566358fb1291edb8659ba42' 
  AND token = 'V4tC8MsJ9Sgpj6o6I38RJkb/KieSEXmuRX1jMUL8iSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}