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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c714e8722f6c2c446ecd17b03d49ef799cf0f1a0fc7470965485bd5385a5249' 
  AND token = 'rXLUUINNM169uf+V13+fY7tsp1MLn7e7RAD0jIv54PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}