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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1398efa5c57ec0fb020c28c53f2d26c364d7b448dbf765eab2f4568e6e9c4761' 
  AND token = 'L8GvAKEEAaDxUteQt6H+5EpZ+U8N7aYMG4G9Ps0mSkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}