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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4d93b5dc74e1f37f4fa15d75a36a48d414cf4cb425c96721ebe996b1d79d322' 
  AND token = '6ec5jT5kqGvdjvJn45TkT5MOPwajJ5BCDcQ7jFhW9kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}