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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a3ac56ed7f744fa7176230075266dd84580856b6f1b94b09d0e2a970cd6ae1f' 
  AND token = 'u+gp03wPgFF4EFcY1QEvzwixjVMPeSv6eb5FPfRwdcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}