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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa49eff4ab829574812fdd6b5ed692b7db9f56268f129649c67a6e6211d2a6f8' 
  AND token = 'xQDZZC2Nfnwhg1yhxpqA+oAAED+yWKO9xwYT1Fryy3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}