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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '447ab98d3d6752fcde949a39075d7b33422f799808f46dd8db35ca3a5e9bcdba' 
  AND token = 'YJS9zLllO4mfYBSaduL6fJ/p3eUC0uGSDdB1XVaPilI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}