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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f173c9bb4a2b86005ab1f826f5bb987e30db87e803d88a0e15afb9f63f920522' 
  AND token = 'M8sVJwYeqFb+tlLHOHaMrjh6/EN55lmOyG3FExUFxm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}