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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d45766dbf14d47be4f5427da961f4bed383fb0ddf4196a961702d07d55096e9' 
  AND token = 'o+z8z0LOBN1Z3/1quPtmnVGfSUROyqX/3LXkAhT7564=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}