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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6061bd3697f8f0fb8be49024eac52a65cd2ea4b1719e128e7db80f5c56c0c3a3' 
  AND token = 'PrH3LDY4RSIgLWpmoqdPDmt5h8e/jbkzB95rPf7hWZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}