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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5567ac621e80cc2ee310e5e803bb71366d278adb49be659898d4fe470aee0725' 
  AND token = 'dFgCVfairBch5WoTALZN4j9DJ9LIV0Jj3Tnz9P0JPr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}