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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d6d7155b850976bc9a06b6c4d477e4d9862bdbd27a0d56d0136a5b91cff6db' 
  AND token = 'CBU1pGspxHw+v8DbsQHlH7OfGWvc2fSblWSVhFGugTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}