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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4c10684ee346a00267c3ae29f2ed1a9bda2f75d087e90606b328b371edef71b' 
  AND token = '+aDnXQEIMJsyL2X+I9ilL7ojGKDCAWft8e4W14jPTSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}