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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e459e64e691ff37ab32138ef6d203a3557a59fd4e7ce3a51c8154e456e8510' 
  AND token = '2QGC6C14rZBZ9AYYrUxDVynr4vYpGfWRGsHlE2HxKnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}