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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df7c20b22b1dcfbf3ab677673a7ea36ecc09161188ca55f875612d69fa369707' 
  AND token = 'C0Jk9Z6tmz+YrNfBhi/fEINcFlzJMd4Rg4h1ECreI50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}