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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0733d5071573b814731f165874a94fe77462f3eeaad353471092d77301c0b738' 
  AND token = '3akW6DYtTMG2vdu9aOu9yIF8SlhF2lc2D3pt9/qa2WA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}