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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd478c5f8125ad483b990c73c3c424364b53f03c912ff001f81e30a8bdbff970f' 
  AND token = 'TcTA4E7G+JjXVcmbHNWL6hcK8rw/6cbgaCfCvS6awVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}