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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8dfc63d7cdb8e267db6cfecb24b26cb8b66f17579c917bf0fd05b30eb0fede' 
  AND token = 'MnWZmU21Vcdd3Qalrf0mJl0Q3qBH1LrcLfdvFkm+Z2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}