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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1755e3f0965cf46b9457c482e78f4f7b7cd428ed367d9fb6582cbe041a77f003' 
  AND token = 'K/h4zBTR45TuIYsJzQHK7zDA7R3gNfXyV1dVQHVWV6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}