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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7127b9162df3d6de265acb0bbf1d4e98f306322e72b3f5b72171db690243d07' 
  AND token = 'Gqhg807J/8mcSRIS81Gtk+7cbm0Ml0x7nw2v+eViZY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}