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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40011d13eb9d53272eb99d39827a57d4c49c52b6c057ec6aba98f479f0e0dbb8' 
  AND token = '0piQb21//h1WyDkD9PIP5P4HtJgPzGiDsqWPq2zU6lI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}