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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee2da3e72c733f55c09504d8956892a263a71d62a7ee43cb4eb5af73c2f62cfa' 
  AND token = 'FSHl/8EVoshtiaRbpwpUf6Xq0OxGcAqfX04afzdUT94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}