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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad435371423abdca1cee816f39924011e69e89411f360610c9f098f66847f06f' 
  AND token = 'pz8VH7RwL9Yt6pOf++bklkKuyJfpgk1EWt++Ldtg9W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}