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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa70dfef19afed6db9e4e771b8c2f6662afefdfda5f0e4d4f2ca0733ff2373a8' 
  AND token = '/D9zUoh5SkRgS0xfkwjdA+LSSfr3sd0Br0NUq6WE6sU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}